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1

Structure and Functional Characterization of Human Histidine Triad Nucleotide-Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia

Shah, Rachit M., Maize, Kimberly M., West, Harrison T., Strom, Alexander M., Finzel, Barry C., Wagner, Carston R.

Journal:

Journal of Molecular Biology

Year:

2018

Language:

english

File:

PDF, 5.60 MB

english, 2018

2

N-(6,7-Dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-d-aspartate receptor antagonists for the treatment of pain

Christopher Deur, Arun K. Agrawal, Heidi Baum, John Booth, Susan Bove, Joan Brieland, Amy Bunker, Cleo Connolly, Joseph Cornicelli, JoAnn Dumin, Barry Finzel, Xinmin Gan, Sheila Guppy, Gregg Kamilar,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 310 KB

english, 2007

3

Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid

Jeffrey A. Pfefferkorn, Meredith L. Greene, Richard A. Nugent, Rebecca J. Gross, Mark A. Mitchell, Barry C. Finzel, Melissa S. Harris, Peter A. Wells, John A. Shelly, Robert A. Anstadt, Robert E. Kilk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 182 KB

english, 2005

4

Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein–Carbohydrate Interaction Inhibitors

Liu, Li-Kai, Finzel, Barry C.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 542 KB

english, 2014

5

Osseous Sarcoidosis Treated With Tumor Necrosis Factor-Inhibitors

Hasni, Sarfaraz A., Kunz, Daniel, Finzel, Kathleen, Gruber, Barry L.

Journal:

Year:

2010

Language:

english

File:

PDF, 664 KB

english, 2010

6

Crystal forms of a lysine-49 phospholipase A2 from the eastern cottonmouth snake

Laura L. Clancy, Timothy J. Rydel, Steven W. Muchmore, Debra R. Holland, Keith D. Watenpaugh, Barry C. Finzel, Howard M. Einspahr

Journal:

Journal of Crystal Growth

Year:

1990

Language:

english

File:

PDF, 253 KB

english, 1990

7

Kinetic and structural characterization of caspase-3 and caspase-8 inhibition by a novel class of irreversible inhibitors

Zhigang Wang, William Watt, Nathan A. Brooks, Melissa S. Harris, Jan Urban, Douglas Boatman, Michael McMillan, Michael Kahn, Robert L. Heinrikson, Barry C. Finzel, Arthur J. Wittwer, James Blinn, Satw

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2010

Language:

english

File:

PDF, 2.04 MB

english, 2010

8

Proteases of enhanced stability: Characteization of a thermostable variant of subtilisin

Philip N. Brayan, Michele L. Rollence, Michael W. Pantoliano, James Wood, Barry C. Finzel, Gary L. Gilliland, Andrew J. Howard, Thomas L. Poulos

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1986

Language:

english

File:

PDF, 3.34 MB

english, 1986

9

Multiple conformations of amino acid residues in ribonuclease A

L. Anders Svensson, Lennart Sjölin, Gary L. Gilliland, Barry C. Finzel, Alexander Wlodawer

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1986

Language:

english

File:

PDF, 520 KB

english, 1986

10

A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 Å Streptomycs rubiginosus structure with xylitol and D-xylose

Marc Whitlow, Andrew J. Howard, Barry C. Finzel, Thomas L. Poulos, Evon Winborne, Gary L. Gilliland

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1991

Language:

english

File:

PDF, 1.72 MB

english, 1991

11

Identification of Novel Non-Hydroxamate Anthrax Toxin Lethal Factor Inhibitors by Topomeric Searching, Docking and Scoring, and in Vitro Screening

Chiu, Ting-Lan, Solberg, Jonathan, Patil, Satish, Geders, Todd W., Zhang, Xia, Rangarajan, Subhashree, Francis, Rawle, Finzel, Barry C., Walters, Michael A., Hook, Derek J.

Journal:

Journal of Chemical Information and Modeling

Year:

2009

Language:

english

File:

PDF, 2.98 MB

english, 2009

12

Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis

Benjamin P. Duckworth, Todd W. Geders, Divya Tiwari, Helena I. Boshoff, Paul A. Sibbald, Clifton E. Barry III, Dirk Schnappinger, Barry C. Finzel, Courtney C. Aldrich

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 519 KB

english, 2011

13

Cation binding to the integrin CD11b I domain and activation model assessment

Eric T Baldwin, Ronald W Sarver, Garold L Bryant Jr, Kimberly A Curry, Michael B Fairbanks, Barry C Finzel, Robert L Garlick, Robert L Heinrikson, Nancy C Horton, Laura-Lee C Kelley, Ana M Mildner, Jo

Journal:

Year:

1998

Language:

english

File:

PDF, 809 KB

english, 1998

14

The Structure of an RNA/DNA Hybrid: A Substrate of the Ribonuclease Activity of HIV-1 Reverse Transcriptase

Nancy C. Horton, Barry C. Finzel

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 942 KB

english, 1996

15

Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus

Artem G. Evdokimov, Marlene Mekel, Kim Hutchings, Lakshmi Narasimhan, Tod Holler, Teresa McGrath, Bryan Beattie, Eric Fauman, Chunhong Yan, Holly Heaslet, Richard Walter, Barry Finzel, Jeffrey Ohren,

Journal:

Journal of Structural Biology

Year:

2008

Language:

english

File:

PDF, 2.66 MB

english, 2008

16

Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors

Romines, Karen R., Watenpaugh, Keith D., Tomich, Paul K., Howe, W. Jeffrey, Morris, Jeanette K., Lovasz, Kristine D., Mulichak, Anne M., Finzel, Barry C., Lynn, Janet C.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.60 MB

english, 1995

17

High-resolution crystal structure of cytochrome P450cam

Poulos, Thomas L., Finzel, Barry C., Howard, Andrew J.

Journal:

Journal of Molecular Biology

Year:

1987

Language:

english

File:

PDF, 3.03 MB

english, 1987

18

Inhibition of Mycobacterium tuberculosis Transaminase BioA by Aryl Hydrazines and Hydrazides

Dai, Ran, Wilson, Daniel J., Geders, Todd W., Aldrich, Courtney C., Finzel, Barry C.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.72 MB

english, 2014

19

Software for macromolecular crystallography: a user's overview

Finzel, Barry C.

Journal:

Current Opinion in Structural Biology

Year:

1993

Language:

english

File:

PDF, 687 KB

english, 1993

20

Three-Dimensional Structure of an Antibody--Antigen Complex

Steven Sheriff, Enid W. Silverton, Eduardo A. Padlan, Gerson H. Cohen, Sandra J. Smith-Gill, Barry C. Finzel and David R. Davies

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.35 MB

english, 1987

21

The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case

Pantoliano, Michael W., Whitlow, Marc, Wood, Jay F., Rollence, Michele L., Finzel, Barry C., Gilliland, Gary L., Poulos, Thomas L., Bryan, Philip N.

Journal:

Year:

1988

Language:

english

File:

PDF, 1.82 MB

english, 1988

22

Searching for Likeness in a Database of Macromolecular Complexes

Van Voorst, Jeffrey R., Finzel, Barry C.

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 4.36 MB

english, 2013

23

Conserved Core Substructures in the Overlay of Protein–Ligand Complexes

Finzel, Barry C., Akavaram, Ramprasad, Ragipindi, Aravind, Van Voorst, Jeffrey R., Cahn, Matthew, Davis, Malcolm E., Pokross, Matt E., Sheriff, Steven, Baldwin, Eric T.

Journal:

Journal of Chemical Information and Modeling

Year:

2011

Language:

english

File:

PDF, 3.72 MB

english, 2011

24

Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

Poulos, Thomas L., Finzel, Barry C., Howard, Andrew J.

Journal:

Year:

1986

Language:

english

File:

PDF, 1.51 MB

english, 1986

25

A versatile kinetics simulation system

Finzel, Barry C., Moore, John W.

Journal:

Journal of Chemical Education

Year:

1980

Language:

english

File:

PDF, 1.25 MB

english, 1980

26

Mechanism-based Inactivation by Aromatization of the Transaminase BioA Involved in Biotin Biosynthesis in Mycobaterium tuberculosis

Shi, Ce, Geders, Todd W., Park, Sae Woong, Wilson, Daniel J., Boshoff, Helena I., Abayomi, Orishadipe, Barry, Clifton E., Schnappinger, Dirk, Finzel, Barry C., Aldrich, Courtney C.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

27

The Structure of the Carboxyltransferase Component of Acetyl-CoA Carboxylase Reveals a Zinc-Binding Motif Unique to the Bacterial Enzyme †,‡

Bilder, Patrick, Lightle, Sandra, Bainbridge, Graeme, Ohren, Jeffrey, Finzel, Barry, Sun, Fang, Holley, Susan, Al-Kassim, Loola, Spessard, Cindy, Melnick, Michael, Newcomer, Marcia, Waldrop, Grover L.

Journal:

Year:

2006

Language:

english

File:

PDF, 1.62 MB

english, 2006

28

Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding

Maize, Kimberly M., Kurbanov, Elbek K., De La Mora-Rey, Teresa, Geders, Todd W., Hwang, Dong-Jin, Walters, Michael A., Johnson, Rodney L., Amin, Elizabeth A., Finzel, Barry C.

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2014

Language:

english

File:

PDF, 1.70 MB

english, 2014

29

High-resolution crystal structures of alternate forms of the human CD44 hyaluronan-binding domain reveal a site for protein interaction

Liu, Li-Kai, Finzel, Barry

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

30

Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily

Maize, Kimberly M., Wagner, Carston R., Finzel, Barry C.

Journal:

Year:

2013

Language:

english

File:

PDF, 245 KB

english, 2013

31

Cover Picture: Inhibition of Mycobacterium tuberculosis Transaminase BioA by Aryl Hydrazines and Hydrazides (ChemBioChem 4/2014)

Dai, Ran, Wilson, Daniel J., Geders, Todd W., Aldrich, Courtney C., Finzel, Barry C.

Journal:

Year:

2014

Language:

english

File:

PDF, 714 KB

english, 2014

32

Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis

Park, Sae Woong, Casalena, Dominick E., Wilson, Daniel J., Dai, Ran, Nag, Partha P., Liu, Feng, Boyce, Jim P., Bittker, Joshua A., Schreiber, Stuart L., Finzel, Barry C., Schnappinger, Dirk, Aldrich,

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 2.64 MB

english, 2015

33

The structure of the TOG-like domain of Drosophila melanogaster Mast/Orbit

De la Mora-Rey, Teresa, Guenther, Brian D., Finzel, Barry C.

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Year:

2013

Language:

english

File:

PDF, 949 KB

english, 2013

34

Fragment-Based Exploration of Binding Site Flexibility in Mycobacterium tuberculosis BioA

Dai, Ran, Geders, Todd W., Liu, Feng, Park, Sae Woong, Schnappinger, Dirk, Aldrich, Courtney C., Finzel, Barry C.

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 4.16 MB

english, 2015

35

[ACM Press the ACM Conference - Orlando, Florida (2012.10.07-2012.10.10)] Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine - BCB '12 - Rapid efficient macromolecular substructure searching in a cloud

Van Voorst, Jeffrey R., Finzel, Barry C.

Year:

2012

Language:

english

File:

PDF, 120 KB

english, 2012

36

Targeting Mycobacterium tuberculosis Biotin Protein Ligase ( Mt BPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors

Bockman, Matthew R., Kalinda, Alvin S., Petrelli, Riccardo, De la Mora-Rey, Teresa, Tiwari, Divya, Liu, Feng, Dawadi, Surendra, Nandakumar, Madhumitha, Rhee, Kyu Y., Schnappinger, Dirk, Finzel, Barry

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

37

Probing the S2′ Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates

Kurbanov, Elbek K., Chiu, Ting-Lan, Solberg, Jonathan, Francis, Subhashree, Maize, Kimberly M, Fernandez, Jenna, Johnson, Rodney L., Hawkinson, Jon E., Walters, Michael A., Finzel, Barry C., Amin, Eli

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 968 KB

english, 2015

38

Ligand-induced expansion of the S1′ site in the anthrax toxin lethal factor

Maize, Kimberly M., Kurbanov, Elbek K., Johnson, Rodney L., Amin, Elizabeth Ambrose, Finzel, Barry C.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

39

Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1

Shah, Rachit, Strom, Alexander, Zhou, Andrew, Maize, Kimberly M., Finzel, Barry C., Wagner, Carston R.

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

40

Coping With Drought on California Rangelands

Macon, Daniel K., Barry, Sheila, Becchetti, Theresa, Davy, Josh S., Doran, Morgan P., Finzel, Julie A., George, Holly, Harper, John M., Huntsinger, Lynn, Ingram, Roger S., Lancaster, Donald E., Larsen

Journal:

Year:

2016

Language:

english

File:

PDF, 826 KB

english, 2016

41

Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation

Eiden, Carter G., Maize, Kimberly M, Finzel, Barry C., Lipscomb, John D., Aldrich, Courtney C.

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 587 KB

english, 2017

42

Structure-Based Optimization of Pyridoxal 5′-Phosphate (PLP)-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis

Liu, Feng, Dawadi, Surendra, Maize, Kimberly M, Dai, Ran, Park, Sae Woong, Schnappinger, Dirk, Finzel, Barry C., Aldrich, Courtney C.

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

43

Caught Before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1)

Shah, Rachit, Maize, Kimberly M, Zhou, Xin, Finzel, Barry C., Wagner, Carston R.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

44

Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain

Shah, Rachit, Chou, Tsui-Fen, Maize, Kimberly M., Strom, Alexander, Finzel, Barry C., Wagner, Carston R.

Journal:

Biochemical and Biophysical Research Communications

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

45

[Methods in Enzymology] Macromolecular Crystallography Part B Volume 277 || [12] LORE: Exploiting database of known structures

Finzel, Barry C.

Year:

1997

Language:

english

File:

PDF, 2.18 MB

english, 1997

46

Novel ANKH Amino Terminus Mutation (Pro5Ser) Associated With Early-Onset Calcium Pyrophosphate Disease With Associated Phosphaturia

Gruber, Barry L., Couto, Ana Rita, Armas, Jácome Bruges, Brown, Matthew A., Finzel, Kathleen, Terkeltaub, Robert A.

Journal:

JCR Journal of Clinical Rheumatology

Year:

2012

Language:

english

File:

PDF, 681 KB

english, 2012

47

A Crystal Structure-Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides

Maize, Kimberly M, Shah, Rachit, Strom, Alex, Kumarapperuma, Sidath C., Zhou, Andrew Li, Wagner, Carston R., Finzel, Barry C.

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 949 KB

english, 2017

48

[AIP Proceedings of Conference on NASA Centers for Commercial Development of Space - Albuquerque, New Mexico (USA) (8−12 Jan 1995)] AIP Conference Proceedings - Glovebox experiments with malic enzyme on USML-1

Einspahr, Howard M., Clancy, Laura L., Finzel, Barry C., Munson, Sybil H., DeLucas, Lawrence J., Rao, Jaganathan, Cook, Paul F., Harris, Ben G.

Year:

1995

Language:

english

File:

PDF, 609 KB

english, 1995

49

Statewide Cross-Sectional Survey of Cryptosporidium and Giardia in California Cow-Calf Herds

Li, Xunde, Flores, Kristopher A., Barry, Sheila, Becchetti, Theresa A., Doran, Morgan, Finzel, Julie A., Larsen, Royce, Lile, David, McDougald, Neil, Nguyen, Tran, Xiao, Chengling, Atwill, Edward R.

Journal:

Rangeland Ecology & Management

Year:

2019

Language:

english

File:

PDF, 340 KB

english, 2019

50

Statewide Cross-Sectional Survey of Cryptosporidium and Giardia in California Cow-Calf Herds

Li, Xunde, Flores, Kristopher A., Barry, Sheila, Becchetti, Theresa A., Doran, Morgan, Finzel, Julie A., Larsen, Royce, Lile, David, McDougald, Neil, Nguyen, Tran, Xiao, Chengling, Atwill, Edward R.

Journal:

Rangeland Ecology & Management

Year:

2019

File:

PDF, 340 KB

2019